Terbinafine Tablets

Terbinafine 250mg Tablets

• Highly active against Candida spp., Aspergillus spp., Sporothrix schenckii, Penicillium marneffei, Malassezia furfur, Cryptococcus neoformans, Trichosporon spp.
• Produced significantly higher mycological cure rates and significantly better clinical improvement compared to Itraconazole in tinea pedis infection.
• Terbinafine exhibits lower MICs compared to Fluconazole, Itraconazole, and Griseofulvin.
• Terbinafine is a more effective 72% compared to Ketoconazole 64% for the treatment of tinea pedis infection.

Terbinafine is a strong medicine that is part of a group called antifungals, which help fight fungus. It is a tablet used to treat many types of fungal infections on the scalp, body, groin, feet, fingernails, and toenails. This medicine, which you can only get with a prescription, directly attacks fungal infections, making it very good at getting rid of ongoing fungal problems.

It’s important to know that terbinafine works well against fungus, but it doesn’t help with infections caused by bacteria or viruses. The medicine gets rid of the fungus that causes the infection, helping to make the skin and nails healthy again.

What Terbinafine Tablet Is Used For?

Terbinafine tablets help treat many different kinds of fungal infections, like:

• Onychomycosis 
• Jock itch
• Athlete’s foot 
• Tinea corporis 
• Tinea capitis (scalp ringworm)

How to Take Terbinafine Tablets?

• People should take terbinafine tablets just as their doctor told them to.
• You can take the tablets by swallowing them with water, either with food or on an empty stomach.
• It’s a good idea to take them at the same time every day to keep the level steady in your blood.
• Fungal nail infections can take several months to treat.
• If you forgot to take your medicine, take it as soon as you remember, unless it’s almost time for your next dose. You should skip it and keep doing what you usually do. Taking extra pills probably won’t hurt you, but it could cause problems like a stomach ache or feeling dizzy.
• People should stay away from caffeine when taking terbinafine because it might stay in their body longer than normal.

Side Effects of Terbinafine Tablets

Terbinafine tablets can have side effects, but not everyone will feel them. Some usual side effects are:

• Skin rash 
• Diarrhoea 
• Feeling sick to your stomach and throwing up.
• Less desire to eat.
• Loss of taste 

Safety measures

If you are taking terbinafine tablets, there are some important things you need to know:

• Before you begin taking terbinafine, let your doctor know about your medical history, especially if you have kidney problems, immune system issues, or lupus.
• Check-ups with a doctor are important to keep track of how things are going and to watch for any side effects. Blood tests might be needed to look for any bad effects. Patients should tell their doctor if their symptoms get worse or don’t get better.
• Liver Problems: This medicine might cause liver issues, so patients should talk to their doctor about it.
• Sun Protection: Since terbinafine can make your skin more sensitive to sunlight, it’s a good idea to use sunscreen and stay away from tanning beds.
• Drink less alcohol: Drinking too much alcohol can lead to serious problems.
• Patients should talk to their doctor about all other medicines they are taking, including ones they can buy without a prescription and herbal products, before using them.

How Does Terbinafine Tablet Work?

Terbinafine is a type of medicine that fights fungal infections by stopping the production of a substance called ergosterol. It works by stopping an enzyme called squalene epoxidase, which is important for making the cell walls of fungi. This blockage causes less ergosterol and more squalene to build up, making the fungal cell wall weaker.

The medicine easily mixes with fat and builds up in the skin, nails, and body fat. When taken by mouth, terbinafine is well absorbed, but only 40% of it is useful because it gets broken down in the liver before reaching the rest of the body. It reaches the highest amount in the blood after about 2 hours.

Terbinafine sticks tightly to proteins in the blood, especially a protein called serum albumin. The body breaks it down using different enzymes, like CYP2C9 and CYP1A2. Most of the drug is removed from the body through urine, and the rest is eliminated in poop. Its effective half-life is around 36 hours, but it can stay in the skin and fat tissue for a much longer time.

Frequently Asked Questions ( FAQ )

What is terbinafine used for?

Terbinafine is a medicine that helps to kill fungal infections on the scalp, body, groin, feet, and nails. It works well for problems like ringworm, athlete’s foot, and jock itch.

Can I take terbinafine every day?

Yes, you usually take terbinafine tablets once a day. The normal dose is 250 mg, and how long you take it depends on the kind of infection.

Who shouldn’t use terbinafine?

People with liver disease, kidney issues, or past allergic reactions to terbinafine should not use it. Pregnant or breastfeeding women should talk to their doctor before using this.

Can I take Terbinafine at night?

You can take Terbinafine any time of day, but it’s good to take it at the same time every day to keep the amount in your blood steady.

How fast does terbinafine work?

Terbinafine usually begins to work within a few days for skin infections.